2011-2013


2013

  • N-[3a-(4-Bromophenyl)-8b-hydroxy-6,8-dimethoxy-3-phenyl-2,3,3a,8b-tetrahydro-1H-cyclopenta[b ]benzofuran-1-yl]formamide monohydrate.
    Aubert M., Thuaud F., Ribeiro N., Désaubry L., Espinosa E.
    Acta Cryst. E
     
    2013, 69, o52-o53
  • Discovery, Molecular and Pharmacological Characterization of GSA-10, a Novel Small-Molecule Positive Modulator of Smoothened
    Tatiana Gorojankina, Lucile Hoch, Hélène Faure, Hermine Roudaut, Elisabeth Traiffort, Angèle Schoenfelder, Nicolas Girard, André Mann, Fabrizio Manetti, Antonio Solinas, Elena Petricci, Maurizio Taddei, and Martial Ruat
    Molecular Pharmacology
    2013, 83, 1020-1029
  • Asymmetric Three-Component Domino Reaction: An Original Access to Chiral Nonracemic 1,3-Thiazin-2-ones
    Flavie Peudru, Fabien Le Cavelier, Jean-Francois Lohier, Mihaela Gulea and Vincent Reboul
    Org. Lett.
    2013, 15, 5710-5713

    Highlighted in SYNFACTS 2014 by Victor Snieckus, Jane Panteleev (Pfizer), 0320014, 10(2), 0136
  • Ortho-(methylsulfanyl)phenylphosphonates and derivatives: Synthesis and applications as mono- or bidentate ligands for the preparation of platinum complexes
    Matthieu Hamela, Mathieu Lecinq, Mihaela Gulea, Jiří Kozelka
    J. Organomet. Chem.
    2013, 745-746, 206-213
  • Expeditious cascade reactions: controlled syntheses of fenestradienes and cyclooctatrienes under palladium catalysis
    Mélanie Charpenay, Aicha Boudhar, Catherine Hulot, Gaëlle Blond, Jean Suffert 
    Tetrahedron
    2013, 69, 7568-7591
    special issue in honour of Pr Paul A. Wender
  • Prohibitin Ligands in Cell Death and Survival: Mode of Action and Therapeutic Potential,
    Thuaud F, Ribeiro N, Nebigil CG, Désaubry L.
    Chem Biol.
    2013, 20, 316-331

2012

  • Cytochromes P450 CYP94C1 and CYP94B3 catalyze two successive oxidation steps of plant hormone Jasmonoyl-isoleucine for catabolic turnover.
    Heitz, T.; Widemann, E.; Lugan, R.; Miesch, L.; Ullmann, P.; Désaubry, L.; Holder, E.; Grausem, B.; Kandel, S.; Miesch, M.; Werck-Reichhart, D.; Pinot, F.
    J. Biol. Chem.
    2012, 287, 6296–6306.
  • The natural anticancer compounds rocaglamides inhibit the Raf-MEK-ERK pathway by targeting prohibitin 1 and 2.
    Polier, G.; Neumann, J.; Thuaud, F.; Ribeiro, N.; Gelhaus, C.; Schmidt, H.; Giaisi, M.; Köhler, R.; Müller, W. W.; Proksch, P.; Leippe, M.; Janssen, O.; Désaubry, L.; Krammer, P. H.; Li-Weber, M.
    Chem. Biol.
    2012, 19, 1093–1104.
  • Flavaglines as potent anticancer and cytoprotective agents.
    Ribeiro, N.; Thuaud, F.; Bernard, Y.; Gaiddon, C.; Cresteil, T.; Hild, A.; Hirsch, E. C.; Michel, P. P.; Nebigil, C. G.; Désaubry, L.
    J. Med. Chem.
    2012, 55, 10064–10073.
  • Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.
    Solinas, A.; Faure, H.; Roudaut, H.; Traiffort, E.; Schoenfelder, A.; Mann, A.; Manetti, F.; Taddei, M.; Ruat, M.
    J. Med. Chem
    .
    2012, 55, 1559–1571.
  • Trimethoxyarene as a Highly Ionizable Tag for Reaction Analysis by Atmospheric Pressure Photoionization Mass Spectrometry (APPI/MS): Exploration of Heterocyclic Synthesis.
    Bui The Thuong, M.; Catala, C.; Colas, C.; Schaeffer, C.; Van Dorsselaer, A.; Mann, A.; Wagner, A.
    Eur. J. Org. Chem. 2012, 85–92

  • Stereoselective Multicomponent Assembly of Enantiopure Oxazolopiperidines and -azepines.
    Zill, N.; Schoenfelder, A.; Girard, N.; Taddei, M.; Mann, A.
    J. Org. Chem.
    2012, 77, 2246-2253

  • Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6
    Bui The Thuong, M.; Mann, A.; Wagner, A.
    Chem. Commun. 2012, 48, 434-436
  • Search for the Most Primitive Membranes: Some Remaining Problems.
    Nakatani, Y.; Ribeiro, N.; Strieff, S.; Désaubry, L.; Ourisson, G.
    Orig. Life Evol. Biosph.
    2012, 42, 497-501


2011

  • Cyclohydrocarbonylation-Based Strategy toward Poly- Substituted Piperidines.
    Arena, G.; Zill, N; Salvadori, J.; Girard, N.; Mann, A.; Taddei, M.
    Org. Lett.
    2011, 13, 2294–2297
  • Flavaglines Alleviate Doxorubicin Cardiotoxicity: Implication of Hsp27
    Bernard, Y.; Ribeiro, N.; Thuaud, F.; Türkeri, G.; Dirr, R.; Boulberdaa, M.; Nebigil, C.G.; Désaubry, L.; Saks, V.
    PLOS
    ONE
    2011, 6, e25302 (2011).

  • Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
    Cazorla, M.; Prémont, J.; MAnn, A.; Girard, N.; Kellendonk, C.; Rognan, Didier
    J. Clin. Invest. 2011, 121, 1846-1857
  • New Palladium-Catalyzed Cascades: 4-exo-dig Cyclocarbopalladation Reaction Followed by Suzuki-Miyaura or Sonogashira Cross-Coupling
    Charpenay, M.; Boudhar, A.; Siby, A.; Schigand, S.; Blond, G.; Suffert, J.
    Adv. Synth. Catal. 2011, 353, 3151-3156

  • Microwave-Assisted Domino Hydroformylation without Syngas
    Cini, E.; Airiau, E.; Girard, N.; Mann, A.; Salvadori, J.; Taddei, M.
    Synlett 2011, 199-202