Publications
2017
-
Pd and Cu-mediated domino reactions for the synthesis of sulfur heterocycles.
Donnard M., Castanheiro T., Gulea M.
in Targets in Heterocyclic Systems (book chapter), vol. ed. Orazio Attanassi, Perdo Merino et Domenico Spinelli, Societa Chimica Italiana, 2017, vol. 21, 255-276 -
Synthesis of Benzo[c]silole derivatives Bearing a Tetrasubstituted Exocyclic C=C Double Bond by Palladium-Catalyzed Domino Reactions.
Wagner P., Gulea M., Suffert J., Donnard M.
Chem. Eur. J., 2017, 23, 7458-7462 -
Desymmetrizing Hydroformylation of Dihydromuconic Acid Diesters: Application to the Synthesis of (+/-)-Vindeburnol
Salacz L., Charpentier C., Suffert J., Girard N.
J. Org. Chem., 2017, 82, 2257-2262 - Synthesis of original polycycles containing 5, 6 and 7-membered rings through cyclocarbopalladations/CH-activation cascade reactions.
Joussot J., Schoenfelder A., Suffert J., Blond G.
Comptes Rendus Chimie, 2017, 20, 665-681 (OPEN ACCESS) -
Cyclocarbopalladation as a key step in cascade reactions: recent developments.
Blouin S., Blond G., Donnard M., Gulea M., Suffert J.
Synthesis, 2017, 49, 1767-1784 -
Comparative study on the reactivity of propargyl and alkynyl sulfides in Palladium-catalyzed domino reactions
Castanheiro T., Suffert J., Donnard M., Gulea M.
Comptes Rendus Chimie, 2017, 20, 624-633 (OPEN ACCESS) -
Intramolecular inverse electron-demand [4+2] cycloadditions of ynamidyl-tethered pyrimidines: comparative studies in trifluorotoluene and sulfolane
Donnard M., Duret G., Bisseret P., Blanchard N.
Comptes Rendus de Chimie, 2017, 20, 643-647 (OPEN ACCESS) -
Hopping of Palladium: Access to Original Polycyclic Structures Containing Three-, Four-, Five- and Six-Membered Rings
Ghosh N., Maiereanu C., Suffert J., Blond G.
Synlett, 2017, 28, 451-455 -
Synthesis of Sulfur Heterocycles via Domino Metal-Mediated Reactions
Castanheiro T., Suffert J., Donnard M., Gulea M.
Phosphorus Sulfur Silicon Relat. Elem., 2017, 192, 162-165
2016
- Recent Contributions to Hetero Diels-Alder Reactions
Blond G., Gulea M., Mamane V.
Curr. Org. Chem., 2016, 20, 2161 -
A Step-Economical Multicomponent Synthesis of 3D-Shaped Aza-Diketopiperazines and Their Drug-like Chemical Space Analysis
- Synthesis of 3-Substituted Chromones and Quinolones from Enaminones
Joussot J., Schoenfelder A., Larquetoux L., Nicolas M., Suffert J., Blond G.
Synthesis, 2016, 48, 3364-3372 -
Aerobic Copper-Mediated Domino Three-Component Approach to 2-Aminobenzothiazole Derivatives.
Castanheiro T., Suffert J., Gulea M., Donnard M.
Org. Lett., 2016, 18, 2588 (OPEN ACCESS) - Synthesis of Cyclooctatetraenes through a Palladium-Catalyzed Cascade Reaction.
Blouin S., Gandon V., Blond G., Suffert J.
Angew. Chem. Int. Ed., 2016, 55, 7208 -
Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.
Fleury A., Hoch L., Martinez MC, Faure H., Taddei M., Petricci E., Manetti F., Girard N., Mann A., Jacques C., Larghero J., Ruat m., Adriantsitohaina R., LeLay S.
Scientific Reports, 2016, 23479
-
Recent Advances in the Chemistry of Organic Thiocyanates.
Castanheiro T., Suffert J., Donnard M., Gulea M.
Chem. Soc. Rev., 2016, 45, 494-505
2015
- Domino transformations involving an electrocyclization reaction
Suffert J., Gulea M., Blond G., Donnard M.
Science of Synthesis, vol. ed. Scott Snyder, Thieme-Verlag, 2015, vol. 4b Applications of domino transformations in organic synthesis 2, pp93-158. -
Synthesis of alkaloids containing a quinolizidine core by means of strategies based on a hydroformylation reaction
Girard N.
Strategies and Tactics in Organic Synthesis 2015, 11, chapter 8, 235-251.
-
MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the smoothened receptor.
Hoch, L.; Faure, H.; Roudaut, H.; Schoenfelder, A.; Mann, A.; Girard, N.; Bihannic, L.; Ayrault, O.; Petricci, E.; Taddei, M.
FASEB 2015, 19, 1817-1829
2014
- Practical access to aromatic thiocyanates by CuCN-mediated direct aerobic oxidative cyanation of thiophenols and diaryl disulfides.
Castanheiro, T.; Gulea, M.; Donnard, M.; Suffert, J.
Eur. J. Org. Chem., 2014, 2014, 7814-7817. -
Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process.
Regenass, P.; Margathe, J.-F.; Mann, A.; Suffert, J.; Hibert, M.; Girard, N.; Bonnet, D.
Chem. Commun. 2014, 50, 9657–9660. - Cyclocarbopalladation/cross-coupling cascade reactions in sulfide series: access to sulfur heterocycles.
Castanheiro, T.; Donnard, M.; Gulea, M.; Suffert, J.
Org. Lett. 2014, 16, 3060–3063.
-
Electrochemical Access to 8-(1-Phenyl-ethyl)-1,4-dioxa-8-aza-spiro[4.5]decane-7-carbonitrile. Application to the Asymmetric Syntheses of (+)-Myrtine and Alkaloid (+)-241D.
Vu, V. H.; Louafi, F.; Girard, N.; Marion, R.; Roisnel, T.; Dorcet, V.; Hurvois, J.-P.
J. Org. Chem. 2014, 79, 3358–3373. - Copper-catalyzed C-C bond formation in natural product synthesis: elegant and efficient solution to a key bond disconnection
(book chapter)
Nicolas Blanchard; Morgan Donnard
chapter 18 in Copper-Mediated Cross-Coupling Reactions; Evano G.; Blanchard, N. Eds.; John Wiley & Sons: Hoboken, 2014, pp 683-723.
2013
- Discovery, Molecular and Pharmacological Characterization of GSA-10, a Novel Small-Molecule Positive Modulator of Smoothened
Tatiana Gorojankina, Lucile H
och, Hélène Faure, Hermine Roudaut, Elisabeth Traiffort, Angèle Schoenfelder, Nicolas Girard, André Mann, Fabrizio Manetti, Antonio Solinas, Elena Petricci, Maurizio Taddei, and Martial Ruat
Molecular Pharmacology 2013, 83, 1020-1029
- Fenestranes in Synthesis: Unique and Highly Inspiring Scaffolds
Aicha Boudhar, Mélanie Charpenay, Gaëlle Blond and Jean Suffert
Angew. Chem. int. Ed. 2013, 52, 12786-12798
- Asymmetric Three-Component Domino Reaction: An Original Access to Chiral Nonracemic 1,3-Thiazin-2-ones
Flavie Peudru, Fabien Le Cavelier, Jean-Francois Lohier, Mihaela Gulea and Vincent Reboul
Org. Lett. 2013, 15, 5710-5713
Highlighted in SYNFACTS 2014 by Victor Snieckus, Jane Panteleev (Pfizer), 0320014, 10(2), 0136
- Ortho-(methylsulfanyl)phenylphosphonates and derivatives: Synthesis and applications as mono- or bidentate ligands for the preparation of platinum complexes
Matthieu Hamela, Mathieu Lecinq, Mihaela Gulea, Jiří Kozelka
J. Organomet. Chem. 2013, 745-746, 206-213
- Expeditious cascade reactions: controlled syntheses of fenestradienes and cyclooctatrienes under palladium catalysis
Mélanie Charpenay, Aicha Boudhar, Catherine Hulot, Gaëlle Blond, Jean Suffert
Tetrahedron 2013, 69, 7568-7591
special issue in honour of Pr Paul A. Wender
2012
-
Expeditious Economical Synthesis of a New Generation of Substituted [4.6.4.6]
Fenestradienes.
Charpenay, M ; Boudhar, A. ; Blond, G. ; Suffert, J.
Angew. Chem. Int. Ed. 2012, 51, 4379-4382
- Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity.
Solinas, A.; Faure, H.; Roudaut, H.; Traiffort, E.; Schoenfelder, A.; Mann, A.; Manetti, F.; Taddei, M.; Ruat, M.
J. Med. Chem. 2012, 55, 1559–1571. -
Trimethoxyarene as a Highly Ionizable Tag for Reaction Analysis by Atmospheric Pressure Photoionization Mass Spectrometry (APPI/MS): Exploration of Heterocyclic Synthesis.
Bui The Thuong, M.; Catala, C.; Colas, C.; Schaeffer, C.; Van Dorsselaer, A.; Mann, A.; Wagner, A.
Eur. J. Org. Chem. 2012, 85–92 -
Stereoselective Multicomponent Assembly of Enantiopure Oxazolopiperidines and -azepines.
Zill, N.; Schoenfelder, A.; Girard, N.; Taddei, M.; Mann, A.
J. Org. Chem. 2012, 77, 2246-2253 - Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF6
Bui The Thuong, M.; Mann, A.; Wagner, A.
Chem. Commun. 2012, 48, 434-436
2011
- Cyclohydrocarbonylation-Based Strategy toward Poly- Substituted Piperidines.
Arena, G.; Zill, N; Salvadori, J.; Girard, N.; Mann, A.; Taddei, M.
Org. Lett. 2011, 13, 2294–2297 -
Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice
Cazorla, M.; Prémont, J.; MAnn, A.; Girard, N.; Kellendonk, C.; Rognan, Didier -
New Palladium-Catalyzed Cascades: 4-exo-dig Cyclocarbopalladation Reaction Followed by Suzuki-Miyaura or Sonogashira Cross-Coupling
Charpenay, M.; Boudhar, A.; Siby, A.; Schigand, S.; Blond, G.; Suffert, J.
Adv. Synth. Catal. 2011, 353, 3151-3156 - Microwave-Assisted Domino Hydroformylation without Syngas
Cini, E.; Airiau, E.; Girard, N.; Mann, A.; Salvadori, J.; Taddei, M.
Synlett 2011, 199-202
