• Three Cheers for Nitrogen: Aza-DKPs, the Aza Analogues of 2,5-Diketopiperazines
    Maujean T., Girard N., Ganesan A., Gulea M., Bonnet D.
    RSC Adv., 2020, 10, 43358

  • Endocyclic Enamides Derived from Aza‐Diketopiperazines as Olefin Partners in Povarov Reaction: An Access to Tetracyclic N‐Heterocycles
    Maujean T., Chataigner I., Girard N., Gulea M., Bonnet D.
    Eur. J. Org. Chem., 2020, doi:10.1002/ejoc.202001339

  • Gold(I)-Catalyzed Domino Reaction for Furopyrans Synthesis
    Ruch M., Brach N., Galéa R., Wagner P., Blond G.
    Molecules, 2020, 25, 4976

  • Solvent Effect in Gold(I)-Catalyzed Domino Reaction: Access to Furopyrans
    Wagner P., Ghosh N., Gandon V., Blond G.
    Org. Lett., 2020, 22, 18, 7333–7337

  • Synthesis of Medium-Sized Heterocycles by Transition-Metal-Catalyzed Intramolecular Cyclization
    Choury M., Basilio Lopes A., Blond G., Gulea M.
    2020, 25, 3147

  • Sustainable Synthetic Approaches Involving Thiocyanation and Sulfur-Cyanation: An Update
    Gulea M. and Donnard M.
    Current Green Chemistry, 2020, 7, 201-207

  • 1D and 2D Silver-Based Coordination Polymers with Thiomorpholine-4-carbonitrile and Aromatic Polyoxoacids as Coligands: Structure, Photocatalysis, Photoluminescence, and TD- DFT Study
    Ristić P., Todorović T. R., Blagojević V., Klisurić O. R., Marjanović I., B. Barta Holló, Vulić P., Gulea M., Donnard M., Monge M., Rodríguez-Castillo M., López-de-Luzuriaga J. M.  and Filipović N. R.
    Cryst. Growth Des., 2020, 20, 4461–4478

  • Influence of C–H/X (X = S, Cl, N, Pt/Pd) Interactions on the Molecular and Crystal Structures of Pt(II) and Pd(II) Complexes with Thiomorpholine-4-carbonitrile: Crystallographic, Thermal, and DFT Study
    Ristić P., Blagojević V., Janjić G., Rodić M., Vulić P., Donnard M., Gulea M., Chylewska A., Makowski M., Todorović T., Filipović N.
    Cryst. Growth Des.
    , 2020, 20, 3018-3033


  • Ligand-Controlled Regiodivergent Hydroformylation of Ynamides: A Stereospecific and Regioselective Access to 2- and 3-Aminoacroleins
    Wagner P., Donnard M., Girard N.
    Org. Lett., 2019, 10.1021/acs.orglett.9b03566

  • Silver-based monomer and coordination polymer with organic thiocyanate ligand: Structural, computational and antiproliferative activity study
    Filipović N. R., Ristić P., Janjić G. , Klisurić O., Puerta A., Padrón J. M., Donnard M., Gulea M., Todorović
    T. R.
    Polyhedron, 2019, 173, 114132

  • Gold(I)-Catalyzed Synthesis of Furopyrans: Insight into Hetero-Diels–Alder Reactions
    Pertschi R., Wagner P., Ghosh N., Gandon V., Blond, G.
    Org. Lett., 2019, 21, 6084-6088

  • Tandem Double-Cross-Coupling/Hydrothiolation Reaction of 2-Sulfenyl Benzimidazoles with Boronic Acids
    Basilio Lopes A., Choury M., Wagner P., Gulea, M.
    Org. Lett., 2019, 21, 5943-5947

  • Synthesis of Aromatic Rings Embedded in Polycyclic Scaffolds by Triyne Cycloaddition: Competition between Carbonylative and Non-Carbonylative Pathways
    Salacz L., Girard N., Suffert J., Blond G.
    Molecules, 2019, 24, 595 (Open Access)

  • Synthesis of benzimidazole‐fused medium‐sized N,S‐heterocycles via palladium‐catalyzed cyclizations
    Basilio Lopes A., Wagner P., Gulea M.
    Eur. J. Org. Chem., 2019, 1361-1370


  • Synthesis of Polyheterocyclic Tropones by [2+2+2+1] Carbonylative Cycloaddition of Triynes
    Salacz L.
    , Girard N., Blond G., Suffert J.
    Org. Lett., 2018, 20, 3915-3918
  • Molecular Diversity of Cyclooctatetraenes through Palladium-Catalyzed Cascade Reactions
    Blouin S., Pertschi R., Schoenfelder A., Suffert J., Blond G.
    Adv. Synth. Catal.
    , 2018, 360, 2166-2171 (VIP)

  • Synthesis of Sulfur-Containing Exo-Bicyclic Dienes and Their Diels–Alder Reactions To Access Thiacycle-Fused Polycyclic Systems
    Castanheiro T., Schoenfelder A., Donnard M., Chataigner I., Gulea M.
    J. Org. Chem.,
    2018, 83, 4505-4515


  • Pd and Cu-mediated domino reactions for the synthesis of sulfur heterocycles.
    Donnard M., Castanheiro T., Gulea M.
    in Targets in Heterocyclic Systems (book chapter), vol. ed. Orazio Attanassi, Perdo Merino et Domenico Spinelli, Societa Chimica Italiana, 2017, vol. 21, 255-276
  • Synthesis of Benzo[c]silole derivatives Bearing a Tetrasubstituted Exocyclic C=C Double Bond by Palladium-Catalyzed Domino Reactions.
    Wagner P., Gulea M., Suffert J., Donnard M.
    Chem. Eur. J.
    2017, 23, 7458-7462

  • Intramolecular inverse electron-demand [4+2] cycloadditions of ynamidyl-tethered pyrimidines: comparative studies in trifluorotoluene and sulfolane
    Donnard M., Duret G., Bisseret P., Blanchard N.
    Comptes Rendus Chimie, 2017, 20, 643-647 (OPEN ACCESS)
  • Desymmetrizing Hydroformylation of Dihydromuconic Acid Diesters: Application to the Synthesis of (+/-)-Vindeburnol
    Salacz L., Charpentier C., Suffert J., Girard N.
    J. Org. Chem.
    , 2017, 82, 2257-2262

  • Synthesis of original polycycles containing 5, 6 and 7-membered rings through cyclocarbopalladations/CH-activation cascade reactions.
    Joussot J., Schoenfelder A., Suffert J., Blond G.
    Comptes Rendus Chimie, 2017, 20, 665-681 (OPEN ACCESS)
  • Cyclocarbopalladation as a key step in cascade reactions: recent developments.
    Blouin S., Blond G., Donnard M., Gulea M., Suffert J.
    , 2017, 49, 1767-1784

  • Comparative study on the reactivity of propargyl and alkynyl sulfides in Palladium-catalyzed domino reactions
    Castanheiro T., Suffert J., Donnard M., Gulea M.
    Comptes Rendus Chimie, 2017,
    20, 624-633 (OPEN ACCESS)

  • Hopping of Palladium: Access to Original Polycyclic Structures Containing Three-, Four-, Five- and Six-Membered Rings
    Ghosh N., Maiereanu C., Suffert J., Blond G.
    2017, 28, 451-455

  • Synthesis of Sulfur Heterocycles via Domino Metal-Mediated Reactions
    Castanheiro T., Suffert J., Donnard M., Gulea M.
    Phosphorus Sulfur Silicon Relat. Elem.
    , 2017, 192, 162

  • Pro-differentiating effects of a synthetic flavagline on human teratocarcinomal cancer stem-like cells.
    Emhemmed F., Ali Azouaou S., Zhao Q., Appert-Collin A., Bennasroune A., Schini-Kerth V.B., Muller C.D., Désaubry L., Fuhrmann G.
    Cell Biol Toxicol., 2017, ASAP


  • Recent Contributions to Hetero Diels-Alder Reactions
    Blond G., Gulea M., Mamane V.
    Curr. Org. Chem.
    , 2016, 20, 2161

  • A Step-Economical Multicomponent Synthesis of 3D-Shaped Aza-Diketopiperazines and Their Drug-like Chemical Space Analysis
    Regenass P.M., Riché S., Peron F., Rognan D., Hibert M., Girard N., Bonnet D.
    Org. Biomol. Chem.,
    2016, 14, 8859-8863

  • A general and efficient synthesis of 2-pyridones, 2-quinolinones and 1-isoquinolinones from azine-N-oxides.
    Wang D., Zhao J., Wang Y., Hu J., Li L., Miao L., Feng H., Désaubry L;, Yu P.
    Asian J. Org. Chem.
    2016, 5, 1442-1446

  • Molecular pathways: the eIF4F translation initiation complex –new opportunities for cancer treatment.
    Malka-Mahieu H., Newman M., Désaubry L., Robert C., Vagner S.
    Clin Cancer Res.
    , 2016, 22, in press

  • Synergistic effects of eIF4A and MEK inhibitors on proliferation of NRAS-mutant melanoma cell lines.
    Malka-Mahieu H., Girault I., Rubington M., Leriche M., Welsch C., Kamsu-Kom N., Zhao Q., Désaubry L., Vagner S., Robert C.
    Cell cycle
    , 2016, 15, 2405-2409

  • Synthesis of hydroxybenzofurans by condensation of quinones with benzoylacetone: revised structure of the adducts.
    Hammoud H., Zhao Q., Désaubry L. 
    Tetrahedron Lett., 2016,
    57, 4044–4045

  • STAT1 Promotes KRAS Colon Tumor Growth and Susceptibility to Pharmacological Inhibition of Translation Initiation Factor eIF4A.
    Wang S, Darini C, Désaubry L, Koromilas AE.
    Mol Cancer Ther.
    2016,  15, 3055-3063

  • Synthesis of 3-Substituted Chromones and Quinolones from Enaminones
    Joussot J., Schoenfelder A., Larquetoux L., Nicolas M., Suffert J., Blond G.
    Synthesis, 2016, 48, 3364-3372

  • Bioisosteric modification of flavaglines
    Qian Z., Tijeras-Raballand A., de Gramont A., Raymond E., Désaubry L.
    Tetrahedron Lett.
    , 2016, 57, 2943

  • Aerobic Copper-Mediated Domino Three-Component Approach to 2-Aminobenzothiazole Derivatives.
    Castanheiro T., Suffert J., Gulea M., Donnard M.
    Org. Lett., 2016, 18, 2588   (OPEN ACCESS)

  • Synthesis of Cyclooctatetraenes through a Palladium-Catalyzed Cascade Reaction.
    Blouin S., Gandon V., Blond G., Suffert J.
    Angew. Chem. Int. Ed.,
    2016, 55, 7208

  • Recent Advances in the Chemistry of Organic Thiocyanates.
    Castanheiro T., Suffert J., Donnard M., Gulea M.
    Chem. Soc. Rev., 2016, 45, 494-505

  • Flavaglines ameliorate experimental colitis and protect against intestinal epithelial cell apoptosis and mitochondrial dysfunction.
    Han J., Zhao Q., Basmadjian C., Désaubry L., Theiss A.L.
    Inflamm. Bowel Dis
    2016, 22, 55-67

  • Recent advances in the synthesis of flavaglines, a family of potent bioactive natural compounds coming from traditional Chinese medicine.
    Zhao Q., Abou-Hamdan H., Désaubry L.
    Eur. J. Org. Chem.
    , 2016, 5908-5916

  • Hedgehog associated to microparticles inhibits adipocyte differentiation via a non-canonical pathway.
    Fleury A., Hoch L., Martinez MC, Faure H., Taddei M., Petricci E., Manetti F., Girard N., Mann A., Jacques C., Larghero J., Ruat m., Adriantsitohaina R., LeLay S.
    Scientific Reports
    , 2016, 23479



  • Discovery and cardioprotective effects of the first non-peptide agonists of the G protein-coupled prokineticin receptor-1.
    Gasser A., Brogi S., Urayama K., Nishi T., Kurose H., Tafi A., Ribeiro N., Désaubry L., Nebigil CG.
    Plos One.
    2015, 10, e0121027

  • Revision of the synthesis and pharmacological activity of a reported translation inhibitor.
    Basmadjian C., Malka-Mahieu H., Désaubry L.
    Anticancer Agents Med. Chem.
    2015, 15, 1305-1307
  • Flavaglines stimulate transient receptor potential melastatin type 6 (TRPM6) channel activity.
    Blanchard MG., de Baaij J.H.F., Verkaart S.A.J., Lameris A.L., Basmadjian C., Zhao Q., Désaubry L., Bindels R.J.M., Hoenderop JG.
    Plos One 2015, 10, e0119028.


  • MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the smoothened receptor.

    Hoch, L.; Faure, H.; Roudaut, H.; Schoenfelder, A.; Mann, A.; Girard, N.; Bihannic, L.; Ayrault, O.; Petricci, E.; Taddei, M.
    FASEB 2015, 19, 1817-1829
  • Assessment of flavaglines as potential chikungunya virus entry inhibitors.
    Wintachai, P.; Thuaud, F.; Basmadjian, C.; Ubol, S.; Désaubry, L.; Smith, D.R.
    Microbiol. Immunol. 2015, 59, 129-141

  • Exploratory studies toward a synthesis of flavaglines . A novel access to a highly substituted. cyclopentenone intermediate
    Basmadjian, C.; Zhao, Q.; Désaubry, L.
    Tetrahedron Lett.
    2015, 56, 727–730.


  • Practical access to aromatic thiocyanates by CuCN-mediated direct aerobic oxidative cyanation of thiophenols and diaryl disulfides.
    Castanheiro, T.;  Gulea, M.; Donnard, M.; Suffert, J.
    Eur. J. Org. Chem., 2014, 2014, 7814-7817.
  • eIF4F is a key and targetable convergence nexus of multiple resistance mechanisms to anti-RAF and anti-MEK cancer therapies.
    Boussemart, L.; Malka-Mahieu, H.; Girault, I.; Allard, D.; Hemmingsson, O.; Tomasic, G.; Thomas, M.; Basmadjian, C.; Ribeiro, N.; Thuaud, F.; Mateus, C.; Routier, E.; Kamsu-Kom, N.; Agoussi, S.; Eggermont, A. M.; Désaubry, L.; Robert, C.; Vagner, S.
    Nature 2014, 513, 105–109.

  • Diastereoselective synthesis of novel aza-diketopiperazines via a domino cyclohydrocarbonylation/addition process.
    Regenass, P.; Margathe, J.-F.; Mann, A.; Suffert, J.; Hibert, M.; Girard, N.; Bonnet, D.
    Chem. Commun. 2014, 50, 9657–9660.

  • Cyclocarbopalladation/cross-coupling cascade reactions in sulfide series: access to sulfur heterocycles.
    Castanheiro, T.; Donnard, M.; Gulea, M.; Suffert, J.
    Org. Lett.
    2014, 16, 3060–3063.
  • Benzofuran derivatives as anticancer inhibitors of mTOR signaling.
    Salomé, C.; Ribeiro, N.; Chavagnan, T.; Thuaud, F.; Serova, M.; de Gramont, A.; Faivre, S.; Raymond, E.; Désaubry, L.
    Eur. J. Med. Chem.
    2014, 81, 181–191.

  • Cancer wars: natural products strike back.
    Basmadjian, C.; Zhao, Q.; Bentouhami, E.; Djehal, A.; Nebigil, C. G.; Johnson, R. A.; Serova, M.; de Gramont, A.; Faivre, S.; Raymond, E.; Désaubry, L. G.
    Front. Chem.
    2014, 2, 20.

  • Electrochemical Access to 8-(1-Phenyl-ethyl)-1,4-dioxa-8-aza-spiro[4.5]decane-7-carbonitrile. Application to the Asymmetric Syntheses of (+)-Myrtine and Alkaloid (+)-241D.
    Vu, V. H.; Louafi, F.; Girard, N.; Marion, R.; Roisnel, T.; Dorcet, V.; Hurvois, J.-P.
    J. Org. Chem. 2014, 79, 3358–3373.

  • Selective anticancer effects of a synthetic flavagline on human Oct4-expressing cancer stem-like cells via a p38 MAPK-dependent caspase-3-dependent pathway.
    Emhemmed, F.; Ali Azouaou, S.; Thuaud, F.; Schini-Kerth, V.; Désaubry, L.; Muller, C. D.; Fuhrmann, G.
    Biochem. Pharmacol. 2014, 89, 185–196.

  • Benzofuran derivatives as a novel class of inhibitors of mTOR signaling.
    Salomé, C.; Narbonne, V.; Ribeiro, N.; Thuaud, F.; Serova, M.; de Gramont, A.; Faivre, S.; Raymond, E.; Désaubry, L.
    Eur. J. Med. Chem.
    2014, 74, 41–49.

  • Copper-catalyzed C-C bond formation in natural product synthesis: elegant and efficient solution to a key bond disconnection
    (book chapter)

    Nicolas Blanchard; Morgan Donnard
    chapter 18 in Copper-Mediated Cross-Coupling Reactions; Evano G.; Blanchard, N. Eds.; John Wiley & Sons: Hoboken, 2014, pp 683-723.