• New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopam
    Bihel, F. J. J.;Justiniano, H.;Schmitt, M.;Hellal, M.;Ibrahim, M. A.;Lugnier, C. and Bourguignon, J. J.
    Bioorganic & Medicinal Chemistry Letters 2011, 21, 6567-6572


  • Pharmacological characterization of the mouse NPFF2 receptor
    Talmont, F.;Mouledous, L.;Piedra-Garcia, L.;Schmitt, M.;Bihel, F.;Bourguignon, J. J.;Zajac, J. M. and Mollereau, C.
    Peptides 2010, 31, 215-220

  • Prefrontal cortex and reversion of atropine-induced disruption of the degraded contingency effect by antipsychotic agents and N-desmethylclozapine in rats
    Carnicella, S.;Mongeot, A.;Bourguignon, J. J. and Oberling, P.
    International Journal of Neuropsychopharmacology 2010, 13, 109-122


  • The flavonoid dioclein is a selective inhibitor of cyclic nucleotide phosphodiesterase type 1 (PDE1) and a cGMP-dependent protein kinase (PKG) vasorelaxant in human vascular tissue
    Goncalves, R. L.;Lugnier, C.;Keravis, T.;Lopes, M. J.;Fantini, F. A.;Schmitt, M.;Cortes, S. F. and Lemos, V. S.
    European Journal of Pharmacology 2009, 620, 78-83

  • Evolution of a Novel Phenolic Pathway for Pollen Development
    Matsuno, M.;Compagnon, V.;Schoch, G. A.;Schmitt, M.;Debayle, D.;Bassard, J. E.;Pollet, B.;Hehn, A.;Heintz, D.;Ullmann, P.;Lapierre, C.;Bernier, F.;Ehlting, J. and Werck-Reichhart, D.
    Science 2009, 325, 1688-1692

  • Design, synthesis and analgesic properties of novel conformationally-restricted N-acylhydrazones (NAH)
    Kummerle, A. E.;Vieira, M. M.;Schmitt, M.;Miranda, A. L. P.;Fraga, C. A. M.;Bourguignon, J. J. and Barreiro, E. J.
    Bioorganic & Medicinal Chemistry Letters 2009, 19, 4963-4966

  • Complexation with beta-cyclodextrin confers oral activity on the flavonoid dioclein
    Rezende, B. A.;Cortes, S. F.;De Sousa, F. B.;Lula, I. S.;Schmitt, M.;Sinisterra, R. D. and Lemos, V. S.
    International Journal of Pharmaceutics 2009, 367, 133-139

  • Rapid synthesis of imidazo[4,5-b]pyridine containing polycyclics by means of palladium-catalyzed amidation of 2-chloro-3-nitropyridine
    Salome, C.;Schmitt, M. and Bourguignon, J. J.
    Tetrahedron Letters 2009, 50, 3798-3800


  • Cyclic nucleotide phosphodiesterase type 4 inhibitors: Evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere
    Raboisson, P.;Schultz, D.;Muller, C.;Reimund, J. M.;Pinna, G.;Mathieu, R.;Bernard, P.;Do, Q. T.;DesJarlais, R. L.;Justiano, H.;Lugnier, C. and Bourguignon, J. J.
    European Journal of Medicinal Chemistry 2008, 43, 816-829

  • 6-endo-dig Cyclization of heteroarylesters to alkynes promoted by Lewis acid catalyst in the presence of Bronsted acid
    Hellal, M.;Bourguignon, J. J. and Bihel, F. J. J.
    Tetrahedron Letters 2008, 49, 62-65


  • Synthesis and reactivity of 2,3-dihydro-1H-2,3-benzodiazepine-1,4(5H)-dione
    Bihel, F. J. J.;Hellal, M. and Bourguignon, J. J.
    Synthesis-Stuttgart 2007, 24, 3791-3796

  • A novel, conformation-specific allosteric inhibitor of the tachykinin NK2 receptor (NK2R) with functionally selective properties
    Maillet, E. L.;Pellegrini, N.;Valant, C.;Bucher, B.;Hibert, M.;Bourguignon, J. J. and Galzi, J. L.
    Faseb Journal 2007, 21, 2124-2134

  • Neuropeptide FF and neuropeptide VF inhibit GABAergic neurotransmission in parvocellular neurons of the rat hypothalamic paraventricular nucleus
    Jhamandas, J. H.;Simonin, F.;Bourguignon, J. J. and Harris, K. H.
    American Journal of Physiology-Regulatory Integrative and Comparative Physiology 2007, 292, R1872-R1880

  • Synthesis of regiospecifically polysubstituted pyridazinones
    de Araujo-Junior, J. X.;Schmitt, M.;Antheaume, C. and Bourguignon, J. J.
    Tetrahedron Letters 2007, 48, 7817-7820

  • 2-Amino-6-iodo-4-tosyloxypyrimidine: a versatile key intermediate for regioselective functionalization of 2-aminopyrimidines in 4-and 6-positions
    Benderitter, P.;de Arajo, J. X.;Schmitt, M. and Bourguignon, J. J.
    Tetrahedron 2007, 63, 12465-12470

  • Isolation and NMR characterization of the indolomonoterpenoid alkaloids from Aspidosperma pyrifolium.
    de Araujo-Junior, J. X.; Antheaume, C.; Trindade, C.; Schmitt, M.; Bourguignon, J. J. and Santana AEG
    Phytochem. Rev.
    , 2007, 6, 183-188


  • Microwave-assisted cyclic amidine synthesis using TiCl4
    Hellal, M.;Bihel, F.;Mongeot, A. and Bourguignon, J. J.
    Organic & Biomolecular Chemistry 2006, 4, 3142-3146

  • Antiarrhythmogenic and antioxidant effect of the flavonoid dioclein in a model of cardiac ischemia/reperfusion
    Vianna, HR.; Cortes, SF.; Ferreira, AJ.; Capettini, LSA.; Schmitt, M.; Almeida, AP.; Massensini, AR. and Lemos, VS.
    Planta Med
    ., 2006, 72 (4), 300-303

  • RF9, a potent and selective neuropeptide FF receptor antagonist, prevents opioid-induced tolerance associated with hyperalgesia
    Simonin, F.;Schmitt, M.;Laulin, J. P.;Laboureyras, E.;Jhamandas, J. H.;MacTavish, D.;Matifas, A.;Mollereau, C.;Laurent, P.;Parmentier, M.;Kieffer, B. L.;Bourguignon, J. J. and Simonnet, G.
    Proceedings of the National Academy of Sciences of the United States of America 2006, 103, 466-471

  • Sequential regio and chemoselective cross-coupling reactions by means of O-6-tri-isopropylsulfonate of 4-bromo-pyridazine 3,6-dione
    de Araujo-Junior, J. X.;Schmitt, M.;Benderitter, P. and Bourguignon, J. J.
    Tetrahedron Letters 2006, 47, 6125-6128

  • Use of 4-bromo pyridazine 3,6-dione for building 3-amino pyridazine libraries
    Schmitt, M.;de Araujo-Junior, J. X.;Oumouch, S. and Bourguignon, J. J.
    Molecular Diversity 2006, 10, 429-434

  • Stereoselective synthesis of 3 '-substituted 2 '-deoxy C-nucleoside pyrazolo[1,5-a]-1,3,5-triazines and their 5 '-phosphate nucleotides
    Mathieu, R.;Schmitt, M. and Bourguignon, J. J.
    Tetrahedron Letters 2006, 47, 5099-5103

  • Use of polyfunctionalized pyridazines as reactive species for building chemical diversity
    Bourguignon, J. J.;Oumouch, S. and Schmitt, M.
    Current Organic Chemistry 2006, 10, 277-295