Discovery of a Locally and Orally Active CXCL12 Neutraligand (LIT-927) with Anti-inflammatory Effect in a Murine Model of Allergic Airway Hypereosinophilia.

Regenass PAbboud DDaubeuf FLehalle CGizzi PRiché SHachet-Haas MRohmer FGasparik VBoeglin DHaiech JKnehans TRognan DHeissler DMarsol CVilla PGalzi JLHibert MFrossard NBonnet D
Journal of medicinal chemistry. 2018 Aug 28


Optimising experimental research in respiratory diseases: an ERS statement.

Bonniaud PFabre AFrossard NGuignabert CInman MKuebler WMMaes TShi WStampfli MUhlig SWhite EWitzenrath MBellaye PSCrestani BEickelberg OFehrenbach HGuenther AJenkins GJoos GMagnan AMaitre BMaus UAReinhold PVernooy JHJRicheldi LKolb M
The European respiratory journal. 2018 May 17


A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects.

Drieu la Rochelle AGuillemyn KDumitrascuta MMartin CUtard VQuillet RSchneider SDaubeuf FWillemse TMampuys PMaes BUWFrossard NBihel FSpetea MSimonin FBallet S
Pain. 2018 


Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice.

Heck SDaubeuf FLe DDSester MBonnet DBals RFrossard NDinh QT
Neuroimmunomodulation. 2017 Apr 20


Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation.

Bollenbach MSalvat EDaubeuf FWagner PYalcin IHumo MLetellier BBecker LJBihel FBourguignon JJVilla PObrecht AFrossard NBarrot MSchmitt M
European journal of medicinal chemistry. 2018 Jan 31


Towards targeting resolution pathways of airway inflammation in asthma.

Barnig CFrossard NLevy BD
Pharmacology & therapeutics. 2018 Jan 20


Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy.

Tavakoli RNemska SJamshidi PGassmann MFrossard N
Journal of visualized experiments : JoVE. 2017 Sep 25


The role of 5-HT2B receptors in mitral valvulopathy: bone marrow mobilization of endothelial progenitors.

Ayme-Dietrich ELawson RCôté Fde Tapia CDa Silva SEbel CHechler BGachet CGuyonnet JRouillard HStoltz JQuentin EBanas SDaubeuf FFrossard NGasser BMazzucotelli JPHermine OMaroteaux LMonassier L
British journal of pharmacology. 2017 Oct 15


A Fast, Easy, and Customizable Eight-Color Flow Cytometric Method for Analysis of the Cellular Content of Bronchoalveolar Lavage Fluid in the Mouse.

Daubeuf FBecker JAguilar-Pimentel JAEbel CHrabě de Angelis MHérault YFrossard N
Current protocols in mouse biology. 2017 Jun 19


Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.

Dong JAulestia FJAssad Kahn SZeniou MDubois LGEl-Habr EADaubeuf FTounsi NCheshier SHFrossard NJunier MPChneiweiss HNéant IMoreau MLeclerc CHaiech JKilhoffer MC
Biochimica et biophysica acta. Molecular cell research. 2017 Jan 18


Increase of Mast Cell-Nerve Association and Neuropeptide Receptor Expression on Mast Cells in Perennial Allergic Rhinitis.

Le DDSchmit DHeck SOmlor AJSester MHerr CSchick BDaubeuf FFähndrich SBals RFrossard NAl Kadah BDinh QT
Neuroimmunomodulation. 2016 Dec 29


Kinetic mRNA Profiling in a Rat Model of Left-Ventricular Hypertrophy Reveals Early Expression of Chemokines and Their Receptors.

Nemska SMonassier LGassmann MFrossard NTavakoli R
PloS one. 2016 Aug 15


Revascularization of the graft in obliterative bronchiolitis after heterotopic tracheal transplantation.

Nemska SDaubeuf FFrossard N
Physiological reports. 2016 


A strategy to discover decoy chemokine ligands with an anti-inflammatory activity.

Abboud DDaubeuf FDo QTUtard VVilla PHaiech JBonnet DHibert MBernard PGalzi JLFrossard N
Scientific reports. 2015 Oct 07


Mannoside Glycolipid Conjugates Display Anti-inflammatory Activity by Inhibition of Toll-like Receptor-4 Mediated Cell Activation.

Flacher VNeuberg PPoint FDaubeuf FMuller QSigwalt DFauny JDRemy JSFrossard NWagner AMueller CGSchaeffer E
ACS chemical biology. 2015 Sep 30


Protective effect of a Protein Epitope Mimetic CCR10 antagonist, POL7085, in a model of allergic eosinophilic airway inflammation.

Daubeuf FJung FDouglas GJChevalier EFrossard N
Respiratory research. 2015 Jun 27


Discovery and characterization of an endogenous CXCR4 antagonist.

Zirafi OKim KAStändker LMohr KBSauter DHeigele AKluge SFWiercinska EChudziak DRichter RMoepps BGierschik PVas VGeiger HLamla MWeil TBurster TZgraja ADaubeuf FFrossard NHachet-Haas MHeunisch FReichetzeder CGalzi JLPérez-Castells JCanales-Mayordomo AJiménez-Barbero JGiménez-Gallego GSchneider MShorter JTelenti AHocher BForssmann WGBonig HKirchhoff FMünch J
Cell reports. 2015 Apr 23


Differential cytokine profiles upon comparing selective versus classic glucocorticoid receptor modulation in human peripheral blood mononuclear cells and inferior turbinate tissue.

Beck IMVan Crombruggen KHoltappels GDaubeuf FFrossard NBachert CDe Bosscher K
PloS one. 2015 Apr 13


Full-root aortic valve replacement with stentless xenograft achieves superior regression of left ventricular hypertrophy compared to pericardial stented aortic valves.

Tavakoli RAuf der Maur CMueller XSchläpfer RJamshidi PDaubeuf FFrossard N
Journal of cardiothoracic surgery. 2015 Feb 03


Eosinophils and the ovalbumin mouse model of asthma.

Daubeuf FFrossard N
Methods in molecular biology (Clifton, N.J.). 2014 


Multikinase inhibitor sorafenib prevents pressure overload-induced left ventricular hypertrophy in rats by blocking the c-Raf/ERK1/2 signaling pathway.

Daryadel ABogdanova AGassmann MMueller XZünd GSeifert BLehalle CFrossard NTavakoli R
Journal of cardiothoracic surgery. 2014 May 09


Targeting mast cells in inflammatory diseases.

Reber LLFrossard N
Pharmacology & therapeutics. 2014 Jan 31


Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.

Reber LLDaubeuf FPejler GAbrink MFrossard N
Journal of immunology (Baltimore, Md. : 1950). 2014 Jan 22


Cold ischemia with selective anterograde in situ pulmonary perfusion preserves gas exchange and mitochondrial homeostasis and curbs inflammation in an experimental model of donation after cardiac death.

Pottecher JSantelmo NNoll ECharles ALBenahmed MCanuet MFrossard NNamer IJGeny BMassard GDiemunsch P
Transplant international : official journal of the European Society for Organ Transplantation. 2013 Jul 29


An antedrug of the CXCL12 neutraligand blocks experimental allergic asthma without systemic effect in mice.

Daubeuf FHachet-Haas MGizzi PGasparik VBonnet DUtard VHibert MFrossard NGalzi JL
The Journal of biological chemistry. 2013 Feb 28


NMR HRMAS spectroscopy of lung biopsy samples: Comparison study between human, pig, rat, and mouse metabolomics.

Benahmed MAElbayed KDaubeuf FSantelmo NFrossard NNamer IJ
Magnetic resonance in medicine. 2014 Feb 14


Acute Asthma Models to Ovalbumin in the Mouse.

Daubeuf FFrossard N
Current protocols in mouse biology. 2013 Mar 01


The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma.

Reber LLDaubeuf FNemska SFrossard N
PloS one. 2012 Nov 26


A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma.

Reber LLDaubeuf FPlantinga MDe Cauwer LGerlo SWaelput WVan Calenbergh STavernier JHaegeman GLambrecht BNFrossard NDe Bosscher K
Journal of immunology (Baltimore, Md. : 1950). 2012 Mar 05


Prodrugs of a CXC Chemokine-12 (CXCL12) Neutraligand Prevent Inflammatory Reactions in an Asthma Model in Vivo.

Gasparik VDaubeuf FHachet-Haas MRohmer FGizzi PHaiech JGalzi JLHibert MBonnet DFrossard N
ACS medicinal chemistry letters. 2012 Dec 09


Performing Bronchoalveolar Lavage in the Mouse.

Daubeuf FFrossard N
Current protocols in mouse biology. 2012 Jun 01


The assessment of the quality of the graft in an animal model for lung transplantation using the metabolomics 1H high-resolution magic angle spinning NMR spectroscopy.

Benahmed MASantelmo NElbayed KFrossard NNoll ECanuet MPottecher JDiemunsch PPiotto MMassard GNamer IJ
Magnetic resonance in medicine. 2012 Dec 09


The peroxisome proliferator-activated receptor α agonist fenofibrate decreases airway reactivity to methacholine and increases endothelial nitric oxide synthase phosphorylation in mouse lung.

Becker JDelayre-Orthez CFrossard NPons F
Fundamental & clinical pharmacology. 2012 Mar 11


Genetic and pharmacological evaluation of cathepsin s in a mouse model of asthma.

Deschamps KCromlish WWeicker SLamontagne SHuszar SLGauthier JYMudgett JSGuimond ARomand RFrossard NPercival MDSlipetz DTan CM
American journal of respiratory cell and molecular biology. 2011 Sep 20


[Respiratory research conference 2009].

Frossard NCrestani B
Revue des maladies respiratoires. 2010 


Neutralizing endogenous chemokines with small molecules. Principles and potential therapeutic applications.

Galzi JLHachet-Haas MBonnet DDaubeuf FLecat SHibert MHaiech JFrossard N
Pharmacology & therapeutics. 2010 Feb 01


Activation of the lung S1P(1) receptor reduces allergen-induced plasma leakage in mice.

Blé FXCannet CZurbruegg SGérard CFrossard NBeckmann NTrifilieff A
British journal of pharmacology. 2009 Sep 25


Ser276 phosphorylation of NF-kB p65 by MSK1 controls SCF expression in inflammation.

Reber LVermeulen LHaegeman GFrossard N
PloS one. 2009 Feb 06


Thymic stromal lymphopoietin overproduced by keratinocytes in mouse skin aggravates experimental asthma.

Zhang ZHener PFrossard NKato SMetzger DLi MChambon P
Proceedings of the National Academy of Sciences of the United States of America. 2009 Feb 02


Allergen-induced lung inflammation in actively sensitized mice assessed with MR imaging.

Blé FXCannet CZurbruegg SKarmouty-Quintana HBergmann RFrossard NTrifilieff ABeckmann N
Radiology. 2008 Jul 22


Overexpression of functional TrkA receptors after internalisation in human airway smooth muscle cells.

Freund-Michel VFrossard N
Biochimica et biophysica acta. 2008 Jun 23


Small neutralizing molecules to inhibit actions of the chemokine CXCL12.

Hachet-Haas MBalabanian KRohmer FPons FFranchet CLecat SChow KYDagher RGizzi PDidier BLagane BKellenberger EBonnet DBaleux FHaiech JParmentier MFrossard NArenzana-Seisdedos FHibert MGalzi JL
The Journal of biological chemistry. 2008 Jun 13


Suppression of allergen-induced airway inflammation and immune response by the peroxisome proliferator-activated receptor-alpha agonist fenofibrate.

Delayre-Orthez CBecker JAuwerx JFrossard NPons F
European journal of pharmacology. 2008 Nov 28


Inhibition of allergen-induced wheal and flare reactions by levocetirizine and desloratadine.

Frossard NStrolin-Benedetti MPurohit APauli G
British journal of clinical pharmacology. 2008 Oct 29


The nerve growth factor and its receptors in airway inflammatory diseases.

Freund-Michel VFrossard N
Pharmacology & therapeutics. 2008 Aug 22


Regulation of peroxisome proliferator-activated receptor-alpha expression during lung inflammation.

Becker JDelayre-Orthez CFrossard NPons F
Pulmonary pharmacology & therapeutics. 2008 Aug 21


Acid-induced modulation of airway basal tone and contractility: role of acid-sensing ion channels (ASICs) and TRPV1 receptor.

Faisy CPlanquette BNaline ERisse PAFrossard NFagon JYAdvenier CDevillier P
Life sciences. 2007 Sep 04


Role of tachykinin NK3 receptors in the release and effects of nerve growth factor in human isolated bronchi.

Naline EHöglund COVincent FEmonds-Alt XLagente VAdvenier CFrossard N
European journal of pharmacology. 2007 Jan 18


Anti-proliferative effect of Euphorbia stenoclada in human airway smooth muscle cells in culture.

Chaabi MFreund-Michel VFrossard NRandriantsoa AAndriantsitohaina RLobstein A
Journal of ethnopharmacology. 2007 Jul 21


Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?

Becker JDelayre-Orthez CFrossard NPons F
Fundamental & clinical pharmacology. 2006 


Inflammatory conditions increase expression of protease-activated receptor-2 by human airway smooth muscle cells in culture.

Freund-Michel VFrossard N
Fundamental & clinical pharmacology. 2006 


Marked stem cell factor expression in the airways of lung transplant recipients.

Da Silva CAAdda MStern Mde Blay FFrossard NIsrael-Biet D
Respiratory research. 2006 Jun 16


Effect of glucocorticoids on stem cell factor expression in human asthmatic bronchi.

Da Silva CABlay FIsrael-Biet DLaval AMGlasser NPauli GFrossard N
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2006 


Stem cell factor and its receptor c-Kit as targets for inflammatory diseases.

Reber LDa Silva CAFrossard N
European journal of pharmacology. 2006 Feb 17


Stem cell factor expression, mast cells and inflammation in asthma.

Da Silva CAReber LFrossard N
Fundamental & clinical pharmacology. 2006 


[Nerve growth factor (NGF): new role for a neuronal mediator in the airways].

Freund-Michel VFrossard N
Pathologie-biologie. 2006 Nov 23


Exposure to endotoxins during sensitization prevents further endotoxin-induced exacerbation of airway inflammation in a mouse model of allergic asthma.

Delayre-Orthez CBecker Jde Blay FFrossard NPons F
International archives of allergy and immunology. 2005 Oct 10


Potential role of stem cell factor in the asthma control by glucocorticoids.

Da Silva CAFrossard N
Chemical immunology and allergy. 2005 


TrkA signalling pathways in human airway smooth muscle cell proliferation.

Freund-Michel VBertrand CFrossard N
Cellular signalling. 2006 Aug 08


PPARalpha downregulates airway inflammation induced by lipopolysaccharide in the mouse.

Delayre-Orthez CBecker JGuenon ILagente VAuwerx JFrossard NPons F
Respiratory research. 2005 Aug 09


Nerve growth factor is released by IL-1beta and induces hyperresponsiveness of the human isolated bronchus.

Frossard NNaline EOlgart Höglund CGeorges OAdvenier C
The European respiratory journal. 2005 


Regulation of stem cell factor expression in inflammation and asthma.

Da Silva CAFrossard N
Memorias do Instituto Oswaldo Cruz. 2005 Jun 14


Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.

Mbebi CGonzález de Aguilar JLSée VDupuis LFrossard NMercken LPradier LLarmet YLoeffler JP
Neurobiology of disease.  


Expression of substance P and nitric oxide synthase in vagal sensory neurons innervating the mouse airways.

Dinh QTGroneberg DAPeiser CJoachim RAFrossard NArck PCKlapp BFFischer A
Regulatory peptides. 2005 


Expression of tyrosine hydroxylase and neuropeptide tyrosine in mouse sympathetic airway-specific neurons under normal situation and allergic airway inflammation.

Dinh QTGroneberg DAWitt CPeiser CCifuentes LBFrossard NKlapp BFFischer A
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2004 


Similar rapid onset of action and magnitude of effect of fexofenadine and cetirizine as assessed by inhibition of histamine-induced wheal-and-flare reaction.

Purohit AN'Gom ASDeslandes BPauli GFrossard N
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2004 


Dose-dependent effects of endotoxins on allergen sensitization and challenge in the mouse.

Delayre-Orthez Cde Blay FFrossard NPons F
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2004 


Nerve growth factor and its receptors in asthma and inflammation.

Frossard NFreund VAdvenier C
European journal of pharmacology. 2004 


Neurogenic mechanisms in bronchial inflammatory diseases.

Groneberg DAQuarcoo DFrossard NFischer A
Allergy. 2004 


In vivo evaluation of a reverse water-in-fluorocarbon emulsion stabilized with a semifluorinated amphiphile as a drug delivery system through the pulmonary route.

Courrier HMPons FLessinger JMFrossard NKrafft MPVandamme TF
International journal of pharmaceutics. 2004 


Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours.

Purohit AMelac MPauli GFrossard N
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2004 


[Nerve growth factor (NGF) in inflammation and asthma].

Freund VFrossard N
Revue des maladies respiratoires. 2004 


Expression of cytochrome P450 4A mRNA in mouse lung: effect of clofibrate and interleukin-1beta.

Le Bouquin RLugnier AFrossard NPons F
Fundamental & clinical pharmacology. 2004 


Expression of nerve growth factor in the airways and its possible role in asthma.

Freund VFrossard N
Progress in brain research. 2004 


Paradoxical early glucocorticoid induction of stem cell factor (SCF) expression in inflammatory conditions.

Da Silva CAKassel OLebouquin RLacroix EJFrossard N
British journal of pharmacology. 2004 Dec 08


Transcription of stem cell factor (SCF) is potentiated by glucocorticoids and interleukin-1beta through concerted regulation of a GRE-like and an NF-kappaB response element.

Da Silva CAHeilbock CKassel OFrossard N
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2003 Oct 16


Twenty-four-hour activity and consistency of activity of levocetirizine and desloratadine in the skin.

Purohit AMelac MPauli GFrossard N
British journal of clinical pharmacology. 2003 


Transforming growth factor-beta and its role in asthma.

Duvernelle CFreund VFrossard N
Pulmonary pharmacology & therapeutics. 2003 


Expression of cytochromes P450 3A in mouse lung: effects of dexamethasone and pregnenolone 16alpha-carbonitrile.

Haag MFautrel AGuillouzo AFrossard NPons F
Archives of toxicology. 2003 Dec 04


Nerve growth factor levels and localisation in human asthmatic bronchi.

Olgart Höglund Cde Blay FOster JPDuvernelle CKassel OPauli GFrossard N
The European respiratory journal. 2002 


Evaluation of cytotoxicity of new semi-fluorinated amphiphiles derived from dimorpholinophosphate.

Courrier HMKrafft MPButz NPorté CFrossard NRémy-Kristensen AMély YPons FVandamme TF
Biomaterials. 2003 


Increased expression and decreased activity of cytochrome P450 1A1 in a murine model of toluene diisocyanate-induced asthma.

Haag MLeusink-Muis TLe Bouquin RNijkamp FPLugnier AFrossard NFolkerts GPons F
Archives of toxicology. 2002 Aug 21


Upregulation of nerve growth factor expression by human airway smooth muscle cells in inflammatory conditions.

Freund VPons FJoly VMathieu EMartinet NFrossard N
The European respiratory journal. 2002 


Nerve growth factor and asthma.

Olgart Höglund CFrossard N
Pulmonary pharmacology & therapeutics. 2002 


Inhibition by glucocorticoids of the interleukin-1beta-enhanced expression of the mast cell growth factor SCF.

Da Silva CAKassel OMathieu EMassard GGasser BFrossard N
British journal of pharmacology. 2002 


Comparative activity of cetirizine and mizolastine on histamine-induced skin wheal and flare responses at 24 h.

Purohit AMélac MPauli GFrossard N
British journal of clinical pharmacology. 2002 


Nerve growth factor secretion by human lung epithelial A549 cells in pro- and anti-inflammatory conditions.

Pons FFreund VKuissu HMathieu EOlgart CFrossard N
European journal of pharmacology. 2001 


Difference in exposure to airborne major rat allergen (Rat n 1) and to endotoxin in rat quarters according to tasks.

Lieutier-Colas FMeyer PLarsson PMalmberg PFrossard NPauli Gde Blay F
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2001 


Local increase in the number of mast cells and expression of nerve growth factor in the bronchus of asthmatic patients after repeated inhalation of allergen at low-dose.

Kassel Ode Blay FDuvernelle COlgart CIsrael-Biet DKrieger PMoreau LMuller CPauli GFrossard N
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 2001 


Human lung fibroblasts secrete nerve growth factor: effect of inflammatory cytokines and glucocorticoids.

Olgart CFrossard N
The European respiratory journal. 2001 


The stem cell factor, its properties and potential role in the airways.

Kassel Oda Silva CFrossard N
Pulmonary pharmacology & therapeutics. 2001 


Duration of the antihistaminic effect after discontinuation of ebastine.

Frossard NVital-Durand DMounedji NValleteau A
Allergy. 2001 


Twenty-four hours of activity of cetirizine and fexofenadine in the skin.

Purohit ADuvernelle CMelac MPauli GFrossard N
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2001 


New insights into the second generation antihistamines.

Walsh GMAnnunziato LFrossard NKnol KLevander SNicolas JMTaglialatela MTharp MDTillement JPTimmerman H
Drugs. 2001 


Altered expression of lung cytochrome P450 3A1 in rat after exposure to sulfur mustard.

Pons FCalvet JHHaag MRaeppel VKeravis TFrossard N
Pharmacology & toxicology. 2001 


Inhalation of toluene diisocyanate affects cytochrome P450 2B1 expression in rat lung.

Pons FHaag MCorcos LBonnet PGuillouzo ALugnier AFrossard N
Archives of toxicology. 2000 


Activity of ebastine (10 and 20 mg) and cetirizine at 24 hours of a steady state treatment in the skin of healthy volunteers.

Frossard NBenabdesselam OPurohit AMounedji NPauli G
Fundamental & clinical pharmacology.  


[Role of bronchial smooth muscle in inflammation].

Frossard N
Revue des maladies respiratoires. 2000 


Comparing the H1 profile of second-generation antihistamines.

Frossard NWalsh GM
Allergy. 2000 


Effect of toluene diisocyanate and its corresponding amines on viability and growth of human lung fibroblasts in culture.

Pons FFischer AFrossard NLugnier A
Cell biology and toxicology. 1999 


Consistency and efficacy of cetirizine (10 mg) versus ebastine (20 mg) at 4 h on skin reactivity.

Purohit ADuvernelle CMelac MBenabdesselam OPauli GFrossard N
European journal of clinical pharmacology. 1999 


Repeated inhalation of low doses of cat allergen that do not induce clinical symptoms increases bronchial hyperresponsiveness and eosinophil cationic protein levels.

de Blay FKrieger PSpirlet FMoreau LDuvernelle CKassel OKopferschmitt MCGasser BDemangeat CPauli GFrossard N
International archives of allergy and immunology. 1999 


Human bronchial smooth muscle cells in culture produce stem cell factor.

Kassel OSchmidlin FDuvernelle CGasser BMassard GFrossard N
The European respiratory journal. 1999 


Calcitonin gene-related peptide-immunoreactive nerves and neuroendocrine cells after lung transplantation in the rat.

Buvry AYang YRTavakoli RFrossard N
American journal of respiratory cell and molecular biology. 1999 


Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder.

Trevisani MSchmidlin FTognetto MNijkamp FPGies JPFrossard NAmadesi SFolkerts GGeppetti P
British journal of pharmacology. 1999 


Nasal effect of cetirizine and loratadine at 24 hours in patients with allergic rhinitis.

Frossard NBenabdesselam OMelac MGlasser NLacronique JPauli G
American journal of therapeutics. 1998 


[The bronchorelaxant effect of helicidine, a Helix pomatia extract, interferes with prostaglandin E2].

Pons FKoenig MMichelot RMayer MFrossard N
Pathologie-biologie. 1999 


Increase in non-specific bronchial hyperresponsiveness without specific response to isocyanate in isocyanate-induced asthma: a pilot study.

Kopferschmitt-Kubler MCFrossard NRohde GPauli G
Respiratory medicine. 1998 


Up- and down-regulation by glucocorticoids of the constitutive expression of the mast cell growth factor stem cell factor by human lung fibroblasts in culture.

Kassel OSchmidlin FDuvernelle Cde Blay FFrossard N
Molecular pharmacology. 1998 


Serum eosinophil cationic protein measurements in the management of perennial and periodic asthma: a prospective study.

de Blay FPurohit AStenger RGries PHamberger CDavid BFrossard NPauli G
The European respiratory journal. 1998 


Consistency of the efficacy of cetirizine and ebastine on skin reactivity.

Frossard NMelac MBenabdesselam OPauli G
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 1998 


Onset of action in the nasal antihistaminic effect of cetirizine and loratadine in patients with allergic rhinitis.

Frossard NLacronique JMelac MBenabdesselam OBraun JJGlasser NPauli G
Allergy. 1997 


Adenosine reduces airway excitatory non-cholinergic (e-NC) contraction through both A1 and A2 adenosine receptor activation in the guinea pig.

Lagente VBarlinski JCano EFrossard N
Fundamental & clinical pharmacology. 1997 


Phenotypic and quantitative changes in mast cells after syngeneic unilateral lung transplantation in the rat.

Buvry AGarbarg MDimitriadou VRouleau ANewlands GFTavakoli RPoaty VLockhart ASchwartz JCFrossard N
Clinical science (London, England : 1979). 1996 


Activation of the TNF alpha-p55 receptor induces myocyte proliferation and modulates agonist-evoked calcium transients in cultured human tracheal smooth muscle cells.

Amrani YPanettieri RAFrossard NBronner C
American journal of respiratory cell and molecular biology. 1996 


[New hypotheses in asthma: the mastocytes].

Kassel OStevens WFrossard N
Revue de pneumologie clinique. 1996 


Selective recruitment of eosinophils by substance P after repeated allergen exposure in allergic rhinitis.

Fajac IBraunstein GIckovic MRLacronique JFrossard N
Allergy. 1995 


5-HT2-mediated bronchial responses after syngeneic lung transplantation in the rat.

Tavakoli RFrossard N
British journal of pharmacology. 1995 


[Airway neuropeptides--what is their role in physiopathology?].

Frossard NFajac I
Allergie et immunologie. 1995 


Do nasal mast cells release histamine on stimulation with substance P in allergic rhinitis?

Braunstein GBuvry ALacronique JDesjardins NFrossard N
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1994 


Inhibition of substance P-induced microvascular leakage by inhaled methoxamine in rat airways.

Larrazet FChauveau MWeber SLockhart AFrossard N
British journal of pharmacology. 1994 


Cyclosporine does not affect in vitro bronchial smooth muscle contractions in treated Lewis rats.

Tavakoli RDaly RCMcGregor CGFrossard N
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation.  


[Bronchial hyperreactivity: neurogenic factors].

Michoud MCFajac IFrossard N
Revue des maladies respiratoires. 1994 


[Neuropeptides of the nasal innervation and allergic rhinitis].

Fajac IFrossard N
Revue des maladies respiratoires. 1994 


Inhaled substance P induces activation of alveolar macrophages and increases airway responses in the guinea-pig.

Boichot ELagente VPaubert-Braquet MFrossard N
Neuropeptides. 1993 


Effect of 5-lipoxygenase inhibitors on the anti-IgE-induced contraction of passively sensitized human bronchus in vitro.

Poaty VRiquet MLeGall GFrossard N
Journal of lipid mediators. 1993 


Muscarinic receptors after syngeneic unilateral lung transplantation.

Poaty VTavakoli RLockhart AFrossard N
Life sciences. 1993 


Modulation by theophylline and enprofylline of the excitatory non-cholinergic transmission in guinea-pig bronchi.

Barlinski JLockhart AFrossard N
The European respiratory journal. 1992 


Activation of an epithelial neurokinin NK-1 receptor induces relaxation of rat trachea through release of prostaglandin E2.

Devillier PAcker GMAdvenier CMarsac JRegoli DFrossard N
The Journal of pharmacology and experimental therapeutics. 1992 


Inhibition of histamine-induced nasal obstruction by cetirizine in allergic rhinitis.

Braunstein GMalaquin FFajac IMelac MFrossard N
British journal of clinical pharmacology. 1992 


In vitro bronchial hyperresponsiveness after lung transplantation in the rat.

Tavakoli RBuvry ALe Gall GBarbet JPHoussin DLockhart AFrossard N
The American journal of physiology. 1992 


Bronchial responses to substance P after antigen challenge in the guinea-pig: in vivo and in vitro studies.

Boichot ELagente VGall GLCarré CMencia-Huerta JMBraquet PLockhart AFrossard N
Mediators of inflammation. 1992 


Clinical and inflammatory responses to exogenous tachykinins in allergic rhinitis.

Braunstein GFajac ILacronique JFrossard N
The American review of respiratory disease. 1991 


Effect of tachykinins in small human airways.

Frossard NBarnes J
Neuropeptides. 1991 


Effect of inhaled morphine on the bronchial response to isocapnic hyperventilation in patients with allergic asthma.

Mestiri MLurie AFrossard NLockhart AMarsac JStrauch GDessanges JF
European journal of clinical pharmacology. 1991 


Tachykinin receptors and the airways.

Frossard NAdvenier C
Life sciences. 1991 


Modulation of bradykinin responses in airway smooth muscle by epithelial enzymes.

Frossard NStretton CDBarnes PJ
Agents and actions. 1990 


Regulatory mechanisms of the contractile responses of rat airways to immunological stimulation.

Frossard N
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1989 


Influence of epithelium on guinea pig airway responses to tachykinins: role of endopeptidase and cyclooxygenase.

Frossard NRhoden KJBarnes PJ
The Journal of pharmacology and experimental therapeutics. 1989 


Tachykinin-induced phosphoinositide breakdown in airway smooth muscle and epithelium: relationship to contraction.

Grandordy BMFrossard NRhoden KJBarnes PJ
Molecular pharmacology. 1988 


Arachidonic acid metabolites and airway epithelium-dependent relaxant factor.

Tschirhart EFrossard NBertrand CLandry Y
The Journal of pharmacology and experimental therapeutics. 1987 


Mu-opioid receptors modulate non-cholinergic constrictor nerves in guinea-pig airways.

Frossard NBarnes PJ
European journal of pharmacology. 1987 


Epithelial modulation of tracheal smooth muscle response to antigenic stimulation.

Frossard NMuller F
Journal of applied physiology (Bethesda, Md. : 1985). 1986 


Physiological approach of beta receptor coupling to adenylate cyclase in rat airways: ontogenical modification and functional antagonism.

Frossard NLandry Y
The Journal of pharmacology and experimental therapeutics. 1985 


Potential anti-anaphylactic activity of clenbuterol, a beta-agonist with calcium antagonist properties.

Frossard NFrankhuyzen-Sierevogel JCBinck MNoordhoek JLandry Y
Agents and actions. 1985 


Calcium dependent modulation of histamine release from mast cells by sodium and potassium.

Binck MFrossard NLandry Y
Agents and actions. 1985 


Sodium-potassium ATPase inhibition potentiates compound 48/80-induced histamine secretion from mast cells.

Amellal MBinck MFrossard NIlien BLandry Y
British journal of pharmacology. 1984 


Sodium-potassium ATPase, calcium, and immunological histamine release.

Frossard NAmellal MLandry Y
Biochemical pharmacology. 1983 


Comparative effects of beta-agonists on central and peripheral rat airways.

Frossard NLandry Y
European journal of respiratory diseases. Supplement. 1983 


[Mechanisms of asthma. II. Potential pharmacological targets].

Frossard NSchoubrenner CLandry Y
Le Poumon et le coeur.  


Inhibition of antigen-induced histamine release from rat mast cells by a cyclic GMP-phosphodiesterase inhibitor and sodium nitrite.

Frossard NPauli GLandry Y
Agents and actions. 1981 


Effects of cyclic AMP- and cyclic GMP- phosphodiesterase inhibitors on immunological release of histamine and on lung contraction.

Frossard NLandry YPauli GRuckstuhl M
British journal of pharmacology. 1981