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  2. Chémogénomique et Chimie Médicinale (CCM)
  3. Groupe Bihel / Schmitt
  4. Publications

Publications

2025

  • Fluor NMR study of amino acid derived ligand to study TSPO
    Duma et al.
    Biochimie     (2025) . DOI : 10.1016/j.biochi.2025.01.015 (Open Access)

2024

  • Multitarget μ-Opioid Receptor Agonists─Neuropeptide FF Receptor Antagonists Induce Potent Antinociception with Reduced Adverse Side Effects
    De Neve et al.
    Journal of Medicinal Chemistry     (2024) 67, 9, 7603-7619. DOI : 10.3389/fnins.2022.1110163

  • Synthesis, Characterization, and Self-Assembling Properties of New Amphiphilic Dendrons Bearing Branched TRIS-Derived Oligomers as Polar Head Groups
    Desgranges et al.
    Macromolecules     (2024) 9, 57, 4495-4507. DOI : 10.1021/acs.macromol.3c02388

  • The IMS Library : from In-Stock to Virtual
    Kellenberger et al.
    ChemMedChem (2024) 19, 20, e202400381. DOI : 10.1002/cmdc.202400381

  • Ethaverine and Papaverine Target Cyclin-Dependent Kinase 5 and Inhibit Lung Cancer Cell Proliferation and Migration
    Laure et al.
    ACS Pharmacology & Translational Science (2024) 7, 5, 1377-1385. DOI : 10.1021/acsptsci.4c00023

2023

  • New insights into the regulation of Cystathionine beta synthase (CBS), an enzyme involved in intellectual deficiency in Down syndrome
    Conan et al.
    Frontiers in Neuroscience     (2023), 16, 1110163. DOI : 10.3389/fnins.2022.1110163
    PPDF on Univoak

2022

  • In Situ Formation of Cationic π-Allylpalladium Precatalysts in Alcoholic Solvents: Application to C–N Bond Formation
    Quillet R et al.
    ACS Catalysis (2022) DOI : 10.1021/acscatal.1c04641
    PDF on Univoak

  • Identification of 8‐Hydroxyquinoline Derivatives That Decrease Cystathionine Beta Synthase (CBS) Activity
    Conan et al.
    Int. J. Mol. Sci.     (2022), 23, 6769. DOI : 10.3390/ijms23126769
    Post-print PDF on Univoak

2021

  • Identification of an N-acylated-D-Arg-Leu-NH2 Dipeptide as a Highly Selective Neuropeptide FF1 Receptor Antagonist That Potently Prevents Opioid-Induced Hyperalgesia
    Quillet R et al.
    J Med Chem (2021) DOI : 10.1021/acs.jmedchem.1c00256
    Post-print PDF on HAL

  • Comprehensive overview of biased pharmacology at the opioid receptors: biased ligands and bias factors
    De Neve J et al
    RSC Med Chem (2021) DOI : 10.1039/D1MD00041A
    Post-print PDF on Univoak

  • Design, Synthesis and Biological Evaluation of Arylpyridin-2-yl Guanidine Derivatives and Cyclic Mimetics as Novel MSK1 Inhibitors. An Application in an Asthma Model
    Bollenbach M et al
    Molecules (2021) 26, 2, 391 DOI : 10.3390/molecules26020391
    Post-print PDF on Univoak

  • Anti-prion Drugs Targeting the Protein Folding Activity of the Ribosome Reduce PABPN1 Aggregation
    Bamia et al
    Neurotherapeutics (2021) DOI : 10.1007/s13311-020-00992-6
    Post-print PDF on Univoak

  • Synthesis, Antileishmanial Activity and in silico Studies of Aminoguanidine Hydrazones (AGH) and Thiosemicarbazones (TSC) Against Leishmania chagasi Amastigotes
    de Aquino et al.
    Medicinal Chemistry (2021) DOI : 10.2174/1573406417666210216154428

2020

  • Diastereoselective Synthesis of Nonplanar 3-Amino-1,2,4-oxadiazine Scaffold: Structure Revision of Alchornedine
    S-Q Tang, M Leloire, S Schneider, J Mohr, J Bricard, P Gizzi, D Garnier, M Schmitt, and F Bihel
    J. Org. Chem. (2020) DOI: 10.1021/acs.joc.0c01764
    Post-print PDF on HAL

  • POxAP Precatalysts and the Negishi Cross-Coupling Reaction
    Tang S-Q, Schmitt M, Bihel F
    Synthesis (2020) 52, 1, 51-59 DOI: 10.1055/s-0039-1690728
    Post-print PDF on Univoak

  • Minimizing HCN in DIC/Oxyma mediated amide bond forming reactions
    Erny M, Lundqvist M, Rasmussen JH, Ludemann-Hombourger O, Bihel F, Pawlas J
    Org. Process Res. Dev. (2020) DOI: 10.1021/acs.oprd.0c00227
    Pre-print on ChemRxiv : DOI: 10.26434/chemrxiv.12404252.v1

  • From electronic waste to cross-coupling reactions: direct valuation of recycled palladium in micellar catalysis
    Lacanau V, Bonneté F, Wagner P, Schmitt M, Meyer D, Bihel F, Contino-Pepin C, Bourgeois D
    ChemSusChem (2020) DOI: 10.1002/cssc.202001155
    C    over picture : 10.1002/cssc.202002039
    P    ost-print on HAL

  • Indole-3-guanylhydrazone hydrochloride mitigates long-term cognitive impairment in a neonatal sepsis model with involvement of MAPK and NFκB pathways
    Heimfarth L et al
    Neurochem. Internat. (2020) 134, 104646 (DOI : 10.1016/j.neuint.2019.104647)

  • Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review
    Albino SL et al
    Current Pharmaceutical Design (2020) 26, 33 (DOI : 10.2174/1381612826666200701160904)